DERMARIS - Dermatological lighting for photodynamic therapy (PDT)
DERMARIS is a dermatological lighting system dedicated to photodynamic therapy (PDT). Designed to meet the requirements of PDT protocols, it supports dermatologists in delivering their treatments, both in private practices and specialized medical centers.
DERMARIS a lighting system designed for photodynamic therapy (PDT)
Dynamic phototherapy relies on precise protocols that require specifically adapted lighting. Control over light characteristics, uniformity of emission, and light stability are essential factors for supporting dermatological treatments using PDT. The DERMARIS was specially designed to treat actinic keratosis (AK) using dynamic phototherapy (PDT).
Photodynamic therapy (PDT) is a medical technique used to destroy pre-cancerous tissues through the combination of photosensitizing substances and a dedicated light source. Designed to integrate seamlessly into the clinical environment, DERMARIS provides dermatologists with a reliable solution tailored to the implementation of photodynamic therapy treatments, while addressing the clinical and organizational constraints of dermatology practice. This PDT lighting system delivers a constant intensity of 20,000 lux and provides a wide, uniform treatment area (20 cm in diameter). The irradiance spectrum of DERMARIS covers all absorption peaks of the photosensitizing molecule used to eliminate pre-cancerous cells.
DERMARIS
Key features of our DERMARIS PDT dermatological light therapy device
Key advantages of the DERMARIS PDT lighting system
- Ease of use:The light is compact and space-saving, making it easy to position the patient(in less than 2 minutes). Turning off the dome is simple—just tilt it upward to turn it off.
- Patient comfort:the treatment isquiet
- Long-term use: over30,000 treatments possible, with eachtreatment lasting 2 hours
- Sustainable lighting: DERMARIS lighting has a lifespan of 60,000 hours and can be used as examination lighting. In addition, no consumables are required during operation
It should be noted that some recent studies now show results achieved in as little as one hour of treatment.
Clinical studies
In a prospective randomized study conducted in 2026 involving 55 patients and 955 cases of actinic keratosis, the DERMARIS light therapy demonstrated excellent and long-lasting results.
Effectiveness:
72.9% of lesions were completely clear at 3 months with 1 hour of illumination.
76.2% of lesions were completely clear at 6 months with 1 hour of illumination.
Similar results were observed after 2 hours of illumination.
Clinical studies
Pain:
- Average pain score of 1.0 out of 10 after 1 hour.
- Average pain score of 0.8 out of 10 after 2 hours.
Post-treatment tolerance:
The treatment was very well tolerated, with generally mild and transient local skin reactions.
Options
Download the documentation
References
As a private dermatologist, I use dynamic phototherapy to treat actinic keratoses.
Daylight therapy is an effective treatment, but using the DERMARIS lamp from SURGIRIS allows you to perform an equivalent treatment in your office with the same results. This treatment can be performed regardless of weather conditions. This technique can be comfortably performed in your office, both in summer and winter, without being dependent on rainy periods or extreme heat.
I personally own two Dermaris lamps for better treatment of two "keratosis fields" in a small dedicated room. Given the frequency of this condition, this equipment is very cost-effective and useful for patients.
Dermatologist (Joigny)
Frequently Asked Questions
Scientific publications
Antonetti, P., Arisi, M., Pellegrini, C., Artelli, G. L., Zola, A., Bruni, M., Romanò, C., Galli, B., Esposito, M., Calzavara-Pinton, P., & Fargnoli, M. C. (2026). Indoor Daylight Photodynamic Therapy for Actinic Keratosis of the Scalp: Intrapatient Comparison Study of 1-hour versus 2-hour Exposure Time. Dermatology and Therapy, 16(2), 1113–1124.
https://doi.org/10.1007/s13555-025-01567-z
Fronville, M., Creusot, M., & Mordon, S. R. (2023). Is a 4J/cm² PpIX-Weighted Simulated Daylight (SDL-PDT) Dose Still Effective for Photodynamic Therapy of Actinic Keratosis?. Pharmaceuticals (Basel, Switzerland), 16(10), 1454.
https://doi.org/10.3390/ph16101454
Creusot, M., & Mordon, S. (2021). Clinical evaluation of a short illumination duration (1 hour) when performing photodynamic therapy for actinic keratosis using the Dermaris light source. Photodiagnosis and Photodynamic Therapy, 36, 102618.
https://doi.org/10.1016/j.pdpdt.2021.102618
Maire, C., Vignion-Dewalle, A. S., Cartier, H., & Mordon, S. (2020). Artificial white light photodynamic therapy for actinic keratosis: a study of 38 patients in private practice. Journal of the European Academy of Dermatology and Venereology: JEADV, 34(4), e165–e167.
https://doi.org/10.1111/jdv.16112
Clinical trials
Dermatol Ther (Heidelb): Antonetti, P., Arisi, M., Pellegrini, C., Artelli, G. L., Zola, A., Bruni, M., Romanò, C., Galli, B., Esposito, M., Calzavara-Pinton, P., & Fargnoli, M. C. (2026). Indoor Daylight Photodynamic Therapy for Actinic Keratosis of the Scalp: Intrapatient Comparison Study of 1 h versus 2 h Exposure Time. Dermatology and Therapy, 16(2), 1113–1124.
https://doi.org/10.1007/s13555-025-01567-z
WCM 2025 Book of Abstracts (Athens): Antonetti, P., Artelli, G.L., Arisi, M., Bruni, M., Zola, A., Calzavara-Pinton, P., Fargnoli, M.C. (2025). A-610 – Intrapatient comparative study on indoor daylight photodynamic therapy (idl-PDT) with exposure time 1 hour vs 2 hours for the treatment of multiple actinic keratoses of the scalp. ABSTRACT, 3(1).
https://doi.org/10.1016/j.ejcskn.2025.100302
EURO PDT 2019: Schimtz, L. (2019) First clinical experiences with MAL-PDT using an artificial white light irradiation device (Dermaris®) in patients with multiple actinic keratoses of the face and scalp: a split-face study.
EURO PDT 2019: Maire, C., Mordon, S. (2019). Simulated daylight (SDL-PDT) treatment of AK with a new LED white light device: clinical results in a prospective observational pilot series in 30 patients.
https://euro-pdt.org/brussels/program.pdf
EURO PDT 2019: Maire, C., Vignion-Dewalle, A. S., Cartier, H., & Mordon, S. (2020). Artificial white light photodynamic therapy for actinic keratosis: a study of 38 patients in private practice. Journal of the European Academy of Dermatology and Venereology: JEADV, 34(4), e165–e167.
https://doi.org/10.1111/jdv.16112
Annals of Dermatology and Venereology: L. Bergmann, M. Quoniou, S. Dalac Rat, G. Jeudy, C. Bedane (2023). Treatment of Grade I and II actinic keratoses of the face and scalp with one hour of dynamic phototherapy using artificial daylight. Annals of Dermatology and Venereology, 3(8).
https://doi.org/10.1016/j.fander.2023.09.515
Dermatol Ther (Heidelb): Arisi, M., Galli, B., Pisani, E. G., La Rosa, G., Licata, G., Rovaris, S., Tomasi, C., Rossi, M., Venturini, M., Spiazzi, L., & Calzavara-Pinton, P. (2022). Randomized Clinical Trial of Conventional versus Indoor Daylight Photodynamic Therapy for Treatment of Actinic Cheilitis. Dermatology and Therapy, 12(9), 2049–2061.
https://doi.org/10.1007/s13555-022-00783-1
Review articles & scientific studies
Mordon, S., Maire, C. (2021). Photodynamic therapy using artificial white light for the treatment of actinic keratoses. Therapeutic Realities in Dermatology and Venereology.
https://www.realites-dermatologiques.com/feuilletage/therapie-photodynamique-par-lumiere-blanche-artificielle-pour-le-traitement-des-keratoses-actiniques/
Mordon, S., Vignion-Dewalle, A. S., Thecua, E., Vicentini, C., Maire, C., Deleporte, P., Baert, G., Lecomte, F., & Mortier, L. (2018). Can daylight-PDT be performed indoors?. Giornale italiano di dermatologia e venereologia: official journal of the Italian Society of Dermatology and Syphilography, 153(6), 811–816.
https://doi.org/10.23736/S0392-0488.18.05907-2
Morton, C. A., Szeimies, R. M., & Braathen, L. R. (2021). Review of the European Society for Photodynamic Therapy (Euro-PDT) Annual Congress 2020. European Journal of Dermatology: EJD, 31(1), 17–21.
https://doi.org/10.1684/ejd.2021.3973
Creusot, M., & Mordon, S. (2021). Clinical evaluation of a short illumination duration (1 hour) when performing photodynamic therapy for actinic keratosis using the Dermaris light source. Photodiagnosis and Photodynamic Therapy, 36, 102618.
https://doi.org/10.1016/j.pdpdt.2021.102618
Need more information?
We are here to help!
Would you like more information about our products and options? Please don't hesitate to contact us.